FBXO28 Antibody, FITC conjugated

Datasheet

Code	CSB-PA889119LC01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) FBXO28 Polyclonal antibody

Uniprot No.

Q9NVF7

Target Names

FBXO28

Alternative Names

CENP 30 antibody; Centromere protein 30 antibody; F box only protein 28 antibody; F box protein 28 antibody; F-box only protein 28 antibody; Fbx28 antibody; FBX28_HUMAN antibody; FBXO28 antibody; FLJ10766 antibody; KIAA0483 antibody; OTTHUMP00000035597 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human F-box only protein 28 protein (251-368AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.

Gene References into Functions

It was shown on human primary islets that FBXO28 improves pancreatic beta-cell survival under diabetogenic conditions without affecting insulin secretion. PMID: 29587369
Expression levels of TP53BP2, FBXO28, and FAM53A genes were associated with patient survival specifically in ER-positive, TP53-mutated tumors. PMID: 28179588
Fbxo28 regulates topoisomerase IIalpha decatenation activity and plays an important role in maintaining genomic stability. PMID: 27754753
Refinement of the critical region of 1q41q42 microdeletion syndrome identifies FBXO28 as a candidate causative gene for intellectual disability and seizures. PMID: 24357076
Study identified F-box protein, FBXO28 that controls MYC-dependent transcription by non-proteolytic ubiquitylation. Depletion of FBXO28 or overexpression of an F-box mutant unable to support MYC ubiquitylation results in an impairment of MYC-driven transcription, transformation and tumourigenesis. PMID: 23776131

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Subcellular Location

Chromosome, centromere, kinetochore.

Database Links

HGNC: 29046

OMIM: 609100

KEGG: hsa:23219

STRING: 9606.ENSP00000355827

UniGene: Hs.64691

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Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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